Hon patrick obahiagbon biography of albert einstein
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Integrated electrochemical microsystems for genetic detectionofpathogens at the pointofcare.
PubMed
Hsieh, Kuangwen; Ferguson, B Scott; Eisenstein, Michael; Plaxco, Kevin W; Soh, H Tom
2015-04-21
The capacity to achieve rapid, sensitive, specific, quantitative, and multiplexed genetic detectionofpathogens via a robust, portable, point-of-care platform could transform many diagnostic applications. And while contemporary technologies have yet to effectively achieve this goal, the advent of microfluidics provides a potentially viable approach to this end by enabling the integration of sophisticated multistep biochemical assays (e.g., sample preparation, genetic amplification, and quantitative detection) in a monolithic, portable device from relatively small biological samples. Integrated electrochemical sensors offer a particularly promising solution to genetic detection because they do not require optical instrumentation and are readily compatible with both integrated circuit and microfluidic technologies. Nevertheless, the development of generalizable microfluidic electrochemical platforms that integrate sample preparation and amplification as well as quantitative and multiplexed detection remains a challenging and unsolved technical problem. Recognizing this unmet need, w
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“Tomorrow is pregnant.”
Nigerian proverb
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“We break, we bleed…and begin again.”
-Wendelyn
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“I walk with the self-assurance of a sleepwalker towards my destiny.”
-Adolf Hitler
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